Healthy workers as young as 45 at greater Covid risk than workers deemed clinically vulnerable

I. Quantifying the risks to the clinically vulnerable

“Who’s at higher risk from coronavirus”

II. Why are those who are older at such increasing risk?

Many T cells apparently die, and so the body’s reserves are depleted — particularly in those over age 40, in whom the thymus gland, the organ that generates new T cells, has become less efficient.

…The new research may help answer another pressing question: Why is it so rare for a child to get sick from the coronavirus?

Children have highly active thymus glands, the source of new T cells. That may allow them to stay ahead of the virus, making new T cells faster than the virus can destroy them. In older adults, [as mentioned above] the thymus does not function as well.

III. Health Secretary declares those above age 50 at increased risk

Currently available data from the UK indicate that those at greatest risk of severe illness and mortality from COVID-19 includes:

— adults over the age of 50, with the risk increasing with age

— those with underlying co-morbidities including chronic heart disease, chronic kidney disease, chronic pulmonary disease, malignancy, obesity and dementia

Currently available data from the UK indicates that those at greatest risk of severe illness and mortality from COVID-19 are adults over the age of 50 years, with the risk increasing markedly over the age of 70 years.

Certain underlying health conditions may result in a higher risk of serious disease and mortality. Such conditions may include:

— solid organ transplant recipients
— haematological cancers
— certain neurological conditions
— chronic kidney disease
— immunosuppression
— dementia
— stroke
— poorly controlled diabetes
— chronic pulmonary disease
— obesity (BMI greater than 40)
— malignancy
— liver disease

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